“The Skeleton Twins” shows us an entirely new Bill Hader. Well, he’s played opposite Kristin Wiig before, on years of “Saturday Night Live.” And he’s played “gay” before — effeminate voice, mannerisms, etc.

But “Twins” is a dramedy, which means there’s drama with the comedy, as he and Wiig play siblings damaged by their past, lovelorn people we meet as the news of one’s attempted suicide interrupts, by phone, the other’s attempted suicide all the way across the country.

Nice departure for both players, especially Hader, which big screen work has been all comic — “Superbad,” etc.

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