Every so often in the Spanish-Mexican co-production “Friends Till Death” (Amigos Hasta la Muerte) there’s a new situation, plot twist or character reaction so idiotic and tone-deaf that one is forced to recall how stupid the premise of the picture has been from the get-go.

It’s about a marriage that ends when the wife cheats, breaking up a decades-long friendship because she hooked-up with her husband’s best friend.

But years later, it becomes important to that hospital doctor (or lab tech, unclear) ex-wife that they all make-up because the cuckolder has cancer and mere weeks to live.

Maria (Marta Hazas) tells her ex, pub-owner Suso (Javier Veiga, who wrote and directed this debacle) about the fate of their Mexican friend/classmate/lover/cuckolder Nacho (Mauricio Ochmann). But, get this. She DOESN’T tell the patient. And neither does Suso.

How and where could this ever happen? Who in healthcare, even in the most repressive states, would allow it? People who aren’t blood relatives conspiring to ensure that no one tells a former loved-one he’s dying? I mean, even cuckolders have rights, right?

Everything else that doesn’t make sense in a COMMON sense way spins out of this whopper of a “Never would happen.” Maria being willing to fake her way back into a Suso relationship, even though she gets new evidence how that never really worked. Not that Suso can tell.

Maria wants a baby and can’t have one with Suso, so “Let’s have one with Nacho!”

And Suso? He just rolls with it in “It was meant to be” fatalism.

“Life works out that I had to be cuckolded and he had to get terminal cancer,” he shrugs (in Spanish or dubbed into English).

“Friends Till Death” is meant to be a comedy/dramedy, with Maria and Suso breaking the fourth wall and narrating/giving their spin to the camera about all this nonsense, comical bickering and comical brawling included. The Galicia (northwestern Spain) settings are pretty.

But there’s little heart, humor or pathos to any of this.Nothing clicks between the characters or engages the viewer with them.

And every time something else doesn’t play, every slow-to-develop dopey new twist this tale takes, we’re reminded that it hasn’t made sense, pretty much from the start.

Rating: unrated, fisticuffs and profanity

Cast: Marta Hazas, Mauricio Ochmann and Javier Veiga.

Credits: Scripted and directed by Javier Veiga. A Medio Limón film on Amazon Prime

Running time: 1:37